Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640524 | 0.89 | CCNE2 (0.38) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8196145 | 0.79 | CYP1A1 (0.40) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8642584 | 0.71 | BRD4 (0.43) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL435246 | 0.71 | PLK1 (0.57) | HAO1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL6624151 | 0.67 | HAO1 (0.39) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8639382 | 0.66 | MAPK14 (0.44) | GSK3B | |
| SCHEMBL6622736 | 0.66 | MAPK14 (0.44) | CDK2GSK3B | |
| SCHEMBL6623323 | 0.66 | MAPK14 (0.44) | CDK2GSK3B | |
| SCHEMBL8642444 | 0.66 | GSK3B (0.45) | CYP1A2CYP2C9ALOX15HSD17B10GSK3B | |
| SCHEMBL7465548 | 0.65 | PTGS2 (0.54) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |