Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385502 | 0.94 | THRB (0.39) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL228775 | 0.94 | THRB (0.39) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL202550 | 0.91 | THRB (0.45) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL9517386 | 0.90 | THRB (0.46) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL32674609 | 0.90 | THRB (0.46) | THRBTHRATSHRHPGDALDH1A1 | |
| Methacrylic Acid SCHEMBL9099472 | 0.87 | THRB (0.35) | THRBTHRAHPGDALDH1A1HSD17B10 | |
| SCHEMBL32674601 | 0.86 | THRB (0.40) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL8950107 | 0.86 | THRB (0.40) | THRBTHRATSHRHPGDALDH1A1 | |
| Phenol SCHEMBL5441534 | 0.86 | THRB (0.39) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL6473821 | 0.85 | THRB (0.46) | THRBTHRATSHRHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627126-A | THERMOGRAPHY; CROSSLINKED RESIN | RICOH COMPANY, LTD. (JP) | 1997-05-06 | — | — | US | disclosed |