Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11925422 | 0.85 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1SLC6A3 | |
| SCHEMBL8026288 | 0.79 | TSHR (0.44) | KDM4EHSD17B10HPGDALDH1A1MAPT | |
| SCHEMBL982771 | 0.79 | HSD17B10 (0.63) | KDM4EHSD17B10HPGDALDH1A1MTNR1A | |
| SCHEMBL87637 | 0.79 | PTGS2 (0.57) | KDM4EHSD17B10HPGDALDH1A1ACHE | |
| SCHEMBL6254697 | 0.79 | KDM4E (0.63) | KDM4EHSD17B10HPGDALDH1A1SLC6A3 | |
| SCHEMBL6626169 | 0.78 | ELANE (0.46) | KDM4EHSD17B10HPGDALDH1A1ACHE | |
| SCHEMBL8927725 | 0.78 | ACHE (0.59) | KDM4EHSD17B10HPGDALDH1A1ACHE | |
| SCHEMBL6623023 | 0.78 | ELANE (0.46) | KDM4EHSD17B10HPGDALDH1A1ACHE | |
| SCHEMBL8927620 | 0.78 | NCEH1 (0.51) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL19581919 | 0.78 | HSD17B10 (0.41) | KDM4EHSD17B10HPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |