Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926560 | 0.78 | KDM4E (0.59) | ACHEALDH1A1HSD17B10GAALMNA | |
| SCHEMBL92889 | 0.78 | ALDH1A1 (0.61) | ACHEALDH1A1HSD17B10PGRGAA | |
| SCHEMBL9324445 | 0.78 | ALDH1A1 (0.66) | ACHEALDH1A1HSD17B10PGRGAA | |
| SCHEMBL8927729 | 0.78 | ALDH1A1 (0.61) | ACHEALDH1A1HSD17B10PGRGAA | |
| SCHEMBL87637 | 0.78 | PTGS2 (0.57) | ACHEALDH1A1HSD17B10PTGS1MAPK1 | |
| SCHEMBL8927620 | 0.77 | NCEH1 (0.51) | ALDH1A1LMNAKMT2ABCHE | |
| SCHEMBL29728939 | 0.77 | ALDH1A1 (0.59) | ACHEALDH1A1HSD17B10PGRGAA | |
| SCHEMBL29434522 | 0.77 | ALDH1A1 (0.59) | ACHEALDH1A1HSD17B10PGRGAA | |
| SCHEMBL11772785 | 0.77 | ALDH1A1 (0.59) | ACHEALDH1A1HSD17B10PGRGAA | |
| SCHEMBL1525967 | 0.77 | ALDH1A1 (0.59) | ACHEALDH1A1HSD17B10PGRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |