Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 1/20 | 0.56 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897451 | 1.00 | HSD17B7 (0.56) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8938166 | 0.81 | SRD5A1 (0.56) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8938169 | 0.81 | SRD5A1 (0.56) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8926928 | 0.81 | SRD5A1 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8926944 | 0.81 | SRD5A1 (0.52) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7527383 | 0.81 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7527375 | 0.81 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL7529348 | 0.81 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL14046283 | 0.81 | SRD5A1 (0.65) | SRD5A1SRD5A2 | |
| SCHEMBL13656757 | 0.81 | HSD17B7 (0.60) | HSD17B7SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |