Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | DDX3X | O00571 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16488795 | 0.81 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2ADDX3X | |
| SCHEMBL839236 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2632867 | 0.79 | SAE1 (0.68) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17589369 | 0.79 | KMT2A (0.66) | ALDH1A1MAPTMEN1KMT2ADDX3X | |
| SCHEMBL18814669 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7097165 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7477649 | 0.79 | SAE1 (0.50) | ALDH1A1MAPTMEN1KMT2ADDX3X | |
| SCHEMBL28145171 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28332617 | 0.79 | GPR35 (0.50) | ALDH1A1MAPTMEN1KMT2ADDX3X | |
| SCHEMBL8830833 | 0.78 | KMT2A (0.79) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |