SCHEMBL7097165

SCHEMBL7097165

CNC(=O)Nc1cccc(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
CYP1A2 P05177 1/20 0.67
KMT2A Q03164 3/20 0.58
MEN1 O00255 1/20 0.58
BAZ1A Q9NRL2 1/20 0.57
TRPV1 Q8NER1 1/20 0.56
EPHX2 P34913 1/20 0.53
NPC1 O15118 2/20 0.51
TP53 P04637 2/20 0.51
MAPK1 P28482 2/20 0.51
RAB9A P51151 2/20 0.51
NLRP3 Q96P20 3/20 0.51
CNR1 P21554 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
MMP1 P03956 2/20 0.50
MMP2 P08253 2/20 0.50
MMP9 P14780 2/20 0.50
HTT P42858 1/20 0.50
PYGL P06737 1/20 0.50
GRIK1 P39086 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9400341 0.88 ALDH1A1 (0.70) ALDH1A1CYP1A2KMT2AMEN1BAZ1A
SCHEMBL29473476 0.85 ALDH1A1 (0.67) ALDH1A1CYP1A2KMT2AMEN1BAZ1A
SCHEMBL16488795 0.82 MEN1 (0.51) ALDH1A1KMT2AMEN1TP53MAPK1
SCHEMBL7098404 0.82 TP53 (0.68) ALDH1A1CYP1A2KMT2AMEN1BAZ1A
Resorcinol SCHEMBL11044157 0.81 ALDH1A1 (0.57) ALDH1A1CYP1A2KMT2AMEN1RAB9A
SCHEMBL18814669 0.81 ALDH1A1 (0.65) ALDH1A1CYP1A2KMT2AMEN1NPC1
SCHEMBL2632867 0.81 SAE1 (0.68) ALDH1A1KMT2AMEN1EPHX2NPC1
SCHEMBL22025929 0.81 ALDH1A1 (0.61) ALDH1A1CYP1A2KMT2AMEN1BAZ1A
SCHEMBL17589369 0.81 KMT2A (0.66) ALDH1A1KMT2AMEN1EPHX2NPC1
SCHEMBL22588925 0.80 ALDH1A1 (0.83) ALDH1A1CYP1A2KMT2AMEN1BAZ1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784387-B1 PHENOL COMPOUND, REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM, REVERSIBLE THERMOSENSITIVE RECORDING LABEL, REVERSIBLE THERMOSENSITIVE RECORDING MEMBER, AND IMAGE-PROCESSING METHOD RICOH CO LTD (JP) 2013-11-06 EP disclosed
US-7553796-B2 Phenol compound, reversible thermosensitive recording medium, reversible thermosensitive recording label, reversible thermosensitive recording member, image-processing apparatus and image-processing method RICOH COMPANY, LTD. (JP) 2009-06-30 US disclosed
US-20080242539-A1 Phenol Compound, Reversible Thermosensitive Recording Medium, Reversible Thermosensitive Recording Label, Reversible Thermosensitive Recording Member, Image-Processing Apparatus and Image-Processing Method RICOH COMPANY, LTD. (JP) 2008-10-02 US disclosed
US-20070225161-A1 Phenol Compound, Reversible Thermosensitive Recording Medium, Reversible Thermosensitive Recording Label, Reversible Thermosensitive Recording Member, Image-Processing Apparatus and Imaging-Processing Method RICOH COMPANY, LTD. (JP) 2007-09-27 US disclosed
US-7169737-B2 For use in recording materials using a color developing dye, such as thermal sensitive recording material and pressure sensitive copying material, storage stability NIPPON SODA CO., LTD. (JP) 2007-01-30 US disclosed
US-7169737-B2 For use in recording materials using a color developing dye, such as thermal sensitive recording material and pressure sensitive copying material, storage stability NIPPON SODA CO., LTD. (JP) 2007-01-30 US disclosed
EP-0737896-B1 Photosensitive composition and photosensitive planographic printing plate KODAK POLYCHROME GRAPHICS JP (JP) 2003-08-27 EP disclosed
US-5731127-A WEAR RESISTANCE, SOLVENT RESISTANCE DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-03-24 US disclosed
EP-0737896-A2 Photosensitive composition and photosensitive planographic printing plate DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-10-16 EP disclosed
US-4378318-A HERBICIDES SCHERING AKTIENGESELLSCHAFT (DE) 1983-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242539-A1 Phenol Compound, Reversible Thermosensitive Recording Medium, Reversible Thermosensitive Recording Label, Reversible Thermosensitive Recording Member, Image-Processing Apparatus and Image-Processing Method TRPV1, TRPV6, TRPA1 ALDH1A1 638/4885CYP1A2 668/4885KMT2A 2308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.