Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879754 | 0.81 | BACE1 (0.46) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL11156486 | 0.81 | BACE1 (0.53) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL14283859 | 0.79 | BACE1 (0.52) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL11779884 | 0.79 | ALOX5 (0.50) | BACE1HSD17B1HSD17B2ALOX5ALDH1A1 | |
| SCHEMBL7761038 | 0.78 | BACE1 (0.64) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL34690 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL12733105 | 0.77 | BACE1 (0.48) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL8926926 | 0.76 | BACE1 (0.47) | BACE1ALOX5ALDH1A1HPGDBCL2L1 | |
| SCHEMBL31510648 | 0.76 | HNF4A (0.43) | BACE1ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL26632610 | 0.76 | HNF4A (0.43) | BACE1ALDH1A1HPGDBCL2L1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702855-A | Electrophotographic photoconductor containing a mixture of a phenol compound and an organic sulfur-containing compound | RICOH COMPANY, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |