Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 13/20 | 0.54 |
| ▸ | CASP5 | P51878 | 13/20 | 0.54 |
| ▸ | CASP4 | P49662 | 11/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926958 | 1.00 | CASP1 (0.54) | CASP1CASP5CASP4SIGMAR1SLC6A4 | |
| SCHEMBL8912652 | 0.73 | CASP1 (0.58) | CASP1CASP5CASP4SLC6A4SLC6A2 | |
| SCHEMBL9689029 | 0.73 | CASP1 (0.85) | CASP1CASP5CASP4SIGMAR1 | |
| SCHEMBL9702244 | 0.73 | CASP1 (0.64) | CASP1CASP5CASP4SIGMAR1DRD3 | |
| SCHEMBL9755198 | 0.71 | CASP1 (0.60) | CASP1CASP5CASP4 | |
| SCHEMBL9129799 | 0.70 | CASP1 (0.62) | CASP1CASP5CASP4SIGMAR1DRD3 | |
| SCHEMBL9688138 | 0.69 | CASP1 (0.58) | CASP1CASP5CASP4 | |
| SCHEMBL9133699 | 0.69 | CASP1 (0.58) | CASP1CASP5CASP4 | |
| SCHEMBL9690413 | 0.69 | CASP1 (0.58) | CASP1CASP5CASP4 | |
| SCHEMBL9689152 | 0.69 | CASP1 (0.58) | CASP1CASP5CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |