Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 13/20 | 0.58 |
| ▸ | CASP5 | P51878 | 13/20 | 0.58 |
| ▸ | CASP4 | P49662 | 11/20 | 0.58 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891364 | 0.81 | CASP1 (0.49) | CASP1CASP5CASP4GALR2GALR1 | |
| SCHEMBL8890384 | 0.78 | CASP1 (0.54) | CASP1CASP5CASP4SLC6A4 | |
| SCHEMBL8891784 | 0.75 | HRH4 (0.45) | CASP1CASP5CASP4GALR2GALR1 | |
| SCHEMBL8926958 | 0.73 | CASP1 (0.54) | CASP1CASP5CASP4SLC6A2SLC6A4 | |
| SCHEMBL8926969 | 0.73 | CASP1 (0.54) | CASP1CASP5CASP4SLC6A2SLC6A4 | |
| SCHEMBL29291218 | 0.73 | CYP1A2 (0.59) | LMNATSHR | |
| SCHEMBL9689029 | 0.72 | CASP1 (0.85) | CASP1CASP5CASP4 | |
| SCHEMBL9702244 | 0.71 | CASP1 (0.64) | CASP1CASP5CASP4 | |
| SCHEMBL9755201 | 0.71 | MEN1 (0.73) | CASP1CASP5CASP4ALDH1A1LMNA | |
| SCHEMBL7716436 | 0.70 | CASP1 (0.62) | CASP1CASP5CASP4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |