Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108518 | 0.82 | CSNK2A1 (0.44) | CSNK2A1METAP2POLBAKR1C3ALDH1A1 | |
| SCHEMBL28007033 | 0.80 | CSNK2A1 (0.48) | CSNK2A1POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL4286053 | 0.79 | ALDH1A1 (0.53) | POLBAKR1C3ALDH1A1HPGDKMT2A | |
| SCHEMBL8938037 | 0.78 | HTT (0.41) | ALDH1A1HPGDKMT2AGAAHTT | |
| SCHEMBL27992220 | 0.77 | TTR (0.47) | CSNK2A1METAP2POLBAKR1C3ALDH1A1 | |
| SCHEMBL24029058 | 0.75 | CSNK2A1 (0.52) | CSNK2A1POLBAKR1C3ALDH1A1KMT2A | |
| SCHEMBL6644184 | 0.75 | CSNK2A1 (0.52) | CSNK2A1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27822471 | 0.74 | CSNK2A1 (0.50) | CSNK2A1POLBAKR1C3ALDH1A1KMT2A | |
| SCHEMBL24019777 | 0.74 | CSNK2A1 (0.50) | CSNK2A1POLBAKR1C3ALDH1A1KMT2A | |
| SCHEMBL29223121 | 0.74 | PTGS2 (0.46) | ALDH1A1HSD17B10KDM4EMCL1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658939-A | PREVENTION THROMBOSIS IN MAMMALS | CORVAS INTERNATIONAL INC. (US) | 1997-08-19 | — | — | US | disclosed |