Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773371 | 0.82 | ALDH1A1 (0.47) | LMNASLC6A4MAPTKCNH2SLC6A2 | |
| SCHEMBL1641150 | 0.79 | ACP3 (0.48) | LMNASLC6A4ESR1CHRM2CHRM4 | |
| SCHEMBL444327 | 0.78 | TYR (0.46) | HTTLMNABRD4SLC6A4TACR1 | |
| SCHEMBL29486495 | 0.78 | TYR (0.46) | HTTLMNABRD4SLC6A4TACR1 | |
| SCHEMBL8927063 | 0.78 | CSNK2A1 (0.43) | HTTLMNABRD4KMT2ANPSR1 | |
| SCHEMBL23934953 | 0.77 | TACR1 (0.44) | HTTLMNABRD4SLC6A4TACR1 | |
| SCHEMBL14509733 | 0.77 | HTT (0.49) | HTTLMNABRD4SLC6A4TACR1 | |
| SCHEMBL9644312 | 0.77 | HTT (0.41) | HTTLMNABRD4SLC6A4TACR1 | |
| SCHEMBL11045593 | 0.77 | BRD4 (0.43) | HTTLMNABRD4SLC6A4TACR1 | |
| SCHEMBL14509731 | 0.77 | HTT (0.41) | HTTLMNABRD4SLC6A4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |