Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718479 | 0.86 | KMT2A (0.77) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL718478 | 0.86 | KMT2A (0.77) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL10148966 | 0.84 | MAPT (0.81) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL13259325 | 0.79 | LMNA (0.71) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL10149036 | 0.77 | LMNA (0.60) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL8206260 | 0.77 | LMNA (0.68) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL8206264 | 0.77 | LMNA (0.68) | MAPTSMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL10128973 | 0.76 | HPGD (0.68) | MAPTSMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL12700847 | 0.76 | HPGD (0.68) | MAPTSMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL715253 | 0.76 | LMNA (0.81) | MAPTSMN1; SMN2LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641598-A | HAVING HIGH RESISTANCE TO THERMAL AND MECHANICAL SHOCK | RICOH COMPANY, LTD. (JP) | 1997-06-24 | — | — | US | disclosed |