Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563545 | 0.78 | CYP2C19 (0.54) | ALDH1A1CYP2C9CYP2C19HTTLMNA | |
| SCHEMBL10681455 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP2C9CYP2C19HTTLMNA | |
| SCHEMBL11638083 | 0.77 | ALDH1A1 (0.51) | ALDH1A1CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL28655173 | 0.75 | TBXA2R (0.69) | ALDH1A1CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL29832825 | 0.75 | TBXA2R (0.69) | ALDH1A1CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL11633006 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL10642741 | 0.73 | CYP2C9 (0.56) | ALDH1A1CYP2C9CYP2C19HTTLMNA | |
| SCHEMBL11400096 | 0.72 | KDM6B (0.46) | ALDH1A1CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL13971307 | 0.72 | CSNK1A1 (0.46) | ALDH1A1HTTLMNACYP3A4NFKB1 | |
| SCHEMBL16758296 | 0.72 | CYP2C9 (0.62) | ALDH1A1CYP2C9HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608143-A | NUCLEIC ACID PROMOTER FRAGMENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5364780-A | Genetic engineering with DNA and promoters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0463056-A1 | EXTERNAL REGULATION OF GENE EXPRESSION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| WO-1990011361-A1 | EXTERNAL REGULATION OF GENE EXPRESSION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |