Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003501 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2RECQLPOLBTDP1 | |
| SCHEMBL28416832 | 0.79 | ALDH1A1 (0.87) | ALDH1A1SMN1; SMN2RECQLPOLBTDP1 | |
| SCHEMBL840655 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL8369698 | 0.78 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2RECQLPOLBNPC1 | |
| SCHEMBL7094650 | 0.78 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2RECQLPOLBTDP1 | |
| SCHEMBL3826923 | 0.77 | RAB9A (0.43) | ALDH1A1SMN1; SMN2RECQLPOLBNPC1 | |
| SCHEMBL7465385 | 0.77 | GAA (0.53) | ALDH1A1SMN1; SMN2RECQLPOLBNPC1 | |
| SCHEMBL94680 | 0.76 | HPGD (0.50) | ALDH1A1SMN1; SMN2RECQLPOLBNPC1 | |
| SCHEMBL8830517 | 0.76 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2RECQLPOLBTDP1 | |
| SCHEMBL824564 | 0.76 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2RECQLPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |