Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003501 | 0.87 | ALDH1A1 (1.00) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9400389 | 0.87 | NPC1 (0.66) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13804530 | 0.84 | ALDH1A1 (0.64) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29473466 | 0.83 | NPC1 (0.55) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28416832 | 0.81 | ALDH1A1 (0.87) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7254971 | 0.81 | ALDH1A1 (0.72) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9038777 | 0.79 | NPC1 (0.58) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8369698 | 0.79 | ALDH1A1 (0.76) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1951110 | 0.79 | GAA (0.61) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14850288 | 0.79 | GAA (0.71) | ALDH1A1RECQLSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | claimed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| EP-1129689-A2 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| JP-58052280-A | — | — | None | — | — | JP | disclosed |
| JP-59193810-A | — | — | None | — | — | JP | disclosed |
| EP-3400210-B1 | \"MULTI-TARGET\" COMPOUNDS WITH INHIBITORY ACTIVITY TOWARDS HISTONE DEACETYLASES AND TUBULIN POLYMERISATION, FOR USE IN THE TREATMENT OF CANCER | UNIV PARIS SACLAY (FR) | 2021-09-29 | — | — | EP | disclosed |
| US-9845297-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2016-02-04 | — | — | US | disclosed |
| US-9216979-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-12-22 | — | — | US | disclosed |
| US-20130090326-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-7553796-B2 | Phenol compound, reversible thermosensitive recording medium, reversible thermosensitive recording label, reversible thermosensitive recording member, image-processing apparatus and image-processing method | RICOH COMPANY, LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1129689-A2 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | disclosed |
| US-5731127-A | WEAR RESISTANCE, SOLVENT RESISTANCE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0737896-A2 | Photosensitive composition and photosensitive planographic printing plate | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1996-10-16 | — | — | EP | disclosed |
| JP-S59193810-A | HERBICIDE | MITSUBISHI PETROCHEM CO LTD | 1984-11-02 | — | — | JP | disclosed |
| US-4404356-A | USING A 2-HYDROXYPHENYL UREA AS CORING AGENT; STORAGE STABILITY; CASTINGS; MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| JP-S5852280-A | SUBSTITUTED PHENYLUREA DERIVATIVE, ITS PREPARATION, AND SELECTIVE HERBICIDE CONTAINING SAID COMPOUND | NISSAN CHEM IND LTD | 1983-03-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090326-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | MPO, LPO, CAT | ALDH1A1 1117/4885RECQL 1967/4885SMN1; SMN2 3979/4885 |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | ALDH1A1 352/4885RECQL 2602/4885SMN1; SMN2 4369/4885 |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | ALDH1A1 389/4885RECQL 1441/4885SMN1; SMN2 4375/4885 |
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | ALDH1A1 1117/4885RECQL 1967/4885SMN1; SMN2 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.