SCHEMBL8927410

SCHEMBL8927410

Cc1cc(O)c(C(C)(C)c2ccccc2)cc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.53
ESR2 Q92731 7/20 0.53
ALDH1A1 P00352 6/20 0.47
CYP3A4 P08684 4/20 0.47
CNR1 P21554 4/20 0.44
CNR2 P34972 4/20 0.44
ALOX15 P16050 5/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP1A2 P05177 2/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
G6PD P11413 1/20 0.43
PKM P14618 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761035 0.90 ESR1 (0.56) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL9757833 0.89 ESR1 (0.53) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL9073140 0.85 ESR1 (0.54) ESR1ESR2ALDH1A1CYP3A4ALOX15
SCHEMBL8927429 0.85 ALDH1A1 (0.60) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL9070611 0.84 ESR1 (0.47) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL10905122 0.84 ESR1 (0.54) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL8367853 0.80 ESR1 (0.41) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL14283746 0.80 CNR1 (0.49) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL13609972 0.79 ESR1 (0.76) ESR1ESR2ALDH1A1ALOX15KDM4E
SCHEMBL3688880 0.78 CNR1 (0.51) ESR1ESR2ALDH1A1CYP3A4CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7534539-B2 Electrophotographic photoreceptor and image forming apparatus having the same SHARP KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
US-5702855-A Electrophotographic photoconductor containing a mixture of a phenol compound and an organic sulfur-containing compound RICOH COMPANY, LTD. (JP) 1997-12-30 US disclosed