SCHEMBL8927429

SCHEMBL8927429

CC(C)(C)c1cc(O)c(C(C)(C)c2ccccc2)cc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.60
ALOX15 P16050 7/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
CYP1A2 P05177 2/20 0.60
KDM4E B2RXH2 1/20 0.60
MAPT P10636 1/20 0.60
ATP2A2 P16615 1/20 0.60
ATP2A3 Q93084 1/20 0.60
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
CYP3A4 P08684 4/20 0.50
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
TP53 P04637 3/20 0.46
LMNA P02545 2/20 0.46
HPGD P15428 2/20 0.46
CYP2C9 P11712 3/20 0.45
HSD17B10 Q99714 2/20 0.45
NR1I2 O75469 1/20 0.45
MIF P14174 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761035 0.94 ESR1 (0.56) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL10905122 0.88 ESR1 (0.54) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL8927410 0.85 ESR1 (0.53) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL14283746 0.83 CNR1 (0.49) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
Phenol SCHEMBL11597348 0.81 ALDH1A1 (0.68) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL7705085 0.81 ESR1 (0.57) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL11205966 0.81 ALDH1A1 (0.53) ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT
SCHEMBL11153766 0.80 ESR1 (0.43) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL1925358 0.78 ESR1 (0.59) ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E
SCHEMBL123763 0.78 ESR1 (0.59) ALDH1A1ALOX15ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
US-20070054207-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2007-03-08 US disclosed
US-5702855-A Electrophotographic photoconductor containing a mixture of a phenol compound and an organic sulfur-containing compound RICOH COMPANY, LTD. (JP) 1997-12-30 US disclosed
US-4421838-A REDUCTION OF SELENIUM COMPOUND IN DIELECTRIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1983-12-20 US disclosed