SCHEMBL8927447

SCHEMBL8927447

COCCOc1ccc(O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 6/20 0.56
ADRB1 P08588 2/20 0.45
IGF1R P08069 1/20 0.43
ALOX15 P16050 1/20 0.43
NQO2 P16083 1/20 0.42
RELA Q04206 1/20 0.42
INPPL1 O15357 1/20 0.41
AKR1B1 P15121 1/20 0.41
ADRB3 P13945 1/20 0.40
MIF P14174 1/20 0.40
PTPN1 P18031 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107983 0.89 ADRB2 (0.59) ADRB2ADRB1IGF1RALOX15INPPL1
SCHEMBL15387356 0.85 ADRB2 (0.61) ADRB2ADRB1IGF1RALOX15LTA4H
SCHEMBL6244383 0.84 LTA4H (0.58) ADRB2ADRB1LTA4H
SCHEMBL28758417 0.83 KDR (0.47) ADRB2INPPL1MAOADYRK1A
SCHEMBL22382537 0.83 CHEK2 (0.42) ADRB2ALOX15INPPL1MIFTUBB4A
SCHEMBL10469526 0.83 ESR1 (0.42) ADRB2ALOX15INPPL1PTPN1TUBB4A
SCHEMBL27038407 0.83 ALDH1A1 (0.59) ADRB2ALOX15INPPL1MAOADYRK1A
SCHEMBL107216 0.83 ADRB2 (0.62) ADRB2ADRB1IGF1RALOX15LTA4H
SCHEMBL8419687 0.82 ADRB3 (0.45) ADRB2INPPL1ADRB3MAOADYRK1A
SCHEMBL10306201 0.82 POLB (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-20100075252-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed