Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107747 | 0.84 | LMNA (0.62) | TSHRMAPTL3MBTL1CYP3A4KMT2A | |
| SCHEMBL9969969 | 0.83 | TSHR (0.64) | TSHRMAPTABCB11CYP3A4ADRA2B | |
| SCHEMBL4873097 | 0.80 | CA12 (0.58) | L3MBTL1CYP3A4KMT2AALDH1A1LMNA | |
| SCHEMBL8927471 | 0.80 | ACHE (0.55) | TSHRMAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL9561176 | 0.80 | TSHR (0.45) | TSHRMAPTABCB11CYP3A4ADRA2B | |
| SCHEMBL12037981 | 0.79 | CYP3A4 (0.55) | TSHRMAPTABCB11CYP3A4ADRA2B | |
| SCHEMBL514995 | 0.78 | TSHR (0.69) | TSHRMAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL16640624 | 0.78 | MAPT (0.60) | TSHRMAPTABCB11CYP3A4ADRA2B | |
| SCHEMBL9928660 | 0.78 | CYP3A4 (0.66) | TSHRMAPTABCB11CYP3A4ADRA2B | |
| SCHEMBL1780723 | 0.77 | MAPT (0.63) | TSHRMAPTL3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187791-B2 | Lithographic printing plate precursor and plate making method thereof | FUJIFILM CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-20100075252-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |