SCHEMBL16640624

SCHEMBL16640624

COCCOC(=O)c1ccc(C(=O)OC)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
TSHR P16473 4/20 0.58
ABCB11 O95342 1/20 0.57
CYP3A4 P08684 1/20 0.57
ADRA2B P18089 1/20 0.57
OPRD1 P41143 1/20 0.57
SCN5A Q14524 1/20 0.57
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CA12 O43570 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
LOXL2 Q9Y4K0 1/20 0.53
CYP4A11 Q02928 2/20 0.53
HPGD P15428 2/20 0.53
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9969969 0.94 TSHR (0.64) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL15068275 0.94 MAPT (0.64) MAPTTSHRCA1CA2TDP1
SCHEMBL23522273 0.88 MAPT (0.58) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL9928660 0.88 CYP3A4 (0.66) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL19634288 0.87 PLK1 (0.55) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL756904 0.86 ESR1 (0.70) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL17299367 0.86 TSHR (0.56) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL11941322 0.86 TSHR (0.56) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL19400961 0.86 ALDH1A1 (0.70) MAPTTSHRABCB11CYP3A4ADRA2B
SCHEMBL13258383 0.86 TSHR (0.56) MAPTTSHRABCB11CYP3A4ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043700-B2 Polymer compound comprising biomass-derived cyclic monomer and preparation method therefor KOLON INDUSTRIES, INC. (KR) 2024-07-23 US disclosed
US-20230365746-A1 POLYESTER INCLUDING COMPONENT FROM BIOMASS AND METHOD FOR PREPARING THE SAME KOLON INDUSTRIES, INC. (KR) 2023-11-16 US disclosed
EP-4215564-A1 POLYESTER INCLUDING COMPONENT FROM BIOMASS AND METHOD FOR PREPARING SAME Kolon Industries, Inc. (KR) 2023-07-26 EP disclosed
CN-115551973-A Recovery of component hydrogen 伊士曼化工公司 2022-12-30 CN disclosed
CN-115397949-A Chemical recycling of waste plastic materials with improved solvolysis catalysts 伊士曼化工公司 2022-11-25 CN disclosed
EP-3831841-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF S&T Global Inc. (US) 2021-06-09 EP disclosed
EP-3157977-B1 COPOLYESTERIMIDES COMPRISING BIS(2-HYDROXYALKYL)-2,2'-(1,4-PHENYLENE)BIS(1,3-DIOXOISOINDOLINE-5-CARBOXYLATE) AND ARTICLES MADE THEREFROM DUPONT TEIJIN FILMS US LP (US) 2018-07-18 EP disclosed
US-9914816-B2 Methods and materials for depolymerizing polyesters INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-03-13 US disclosed
US-20160060419-A1 METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-03-03 US disclosed
US-9255194-B2 Methods and materials for depolymerizing polyesters INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-02-09 US disclosed
WO-2015056377-A1 METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-23 WO disclosed
US-20150105532-A1 METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043700-B2 Polymer compound comprising biomass-derived cyclic monomer and preparation method therefor GGPS1, NOTUM, FDPS MAPT 1305/4885TSHR 4836/4885ABCB11 3802/4885
US-20150105532-A1 METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS TKT, DERA, KHK MAPT 108/4885TSHR 4044/4885ABCB11 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.