Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927492 | 0.86 | ALB (0.35) | — | |
| SCHEMBL8927153 | 0.85 | — | — | |
| SCHEMBL9178884 | 0.85 | — | — | |
| SCHEMBL8743038 | 0.81 | — | — | |
| SCHEMBL8926331 | 0.78 | FGFR1 (0.36) | — | |
| SCHEMBL8927516 | 0.68 | AHCY (0.53) | ADORA2AADORA2BADORA1 | |
| SCHEMBL27293671 | 0.68 | AHCY (0.53) | ADORA2AADORA2BADORA1 | |
| SCHEMBL8926287 | 0.67 | BLM (0.48) | — | |
| SCHEMBL8743024 | 0.67 | ALB (0.35) | — | |
| SCHEMBL8743028 | 0.67 | ALB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644043-A | ANTITUMOR, ANTICANCER, TREATMENT OF HERPES | ELI LILLY AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| US-5574021-A | LEUKEMIA | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0329348-B1 | 2',3'-Dideoxy-2',2'-difluoronucleosides | LILLY CO ELI (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0329348-A2 | 2',3'-Dideoxy-2',2'-difluoronucleosides | ELI LILLY AND COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |