Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.85 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304425 | 1.00 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL8049692 | 1.00 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL8049689 | 1.00 | MAPT (0.85) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL23377537 | 0.96 | MAPT (0.79) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL9838136 | 0.96 | MAPT (0.79) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL9838141 | 0.96 | MAPT (0.79) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL8614831 | 0.94 | ALDH1A1 (0.81) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL13070554 | 0.93 | KDM4E (0.74) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL11311833 | 0.93 | MAPT (0.73) | MAPTALDH1A1KDM4EHPGDCES2 | |
| SCHEMBL9839256 | 0.92 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4EHPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111763139-A | Pinocembrin, application of pinocembrin and preparation method of pinocembrin | 南通大学 | 2020-10-13 | — | — | CN | claimed |
| US-7709632-B2 | such as porphyrins, chlorins, texaphyrins via cyclization, oligomerization | JOHNSON THOMAS E | 2010-05-04 | — | — | US | claimed |
| CN-111763139-B | Pinocembrin, application of pinocembrin and preparation method of pinocembrin | 苏州擎源生物科技合伙企业(有限合伙) | 2022-11-22 | — | — | CN | disclosed |
| CN-111763139-A | Pinocembrin, application of pinocembrin and preparation method of pinocembrin | 南通大学 | 2020-10-13 | — | — | CN | disclosed |
| EP-1716153-B1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20120157658-A1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E (US) | 2012-06-21 | — | — | US | disclosed |
| US-8053571-B2 | Methods, compositions, and apparatuses for forming macrocyclic compounds | JOHNSON THOMAS E | 2011-11-08 | — | — | US | disclosed |
| US-20100216970-A1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E | 2010-08-26 | — | — | US | disclosed |
| US-7709632-B2 | such as porphyrins, chlorins, texaphyrins via cyclization, oligomerization | JOHNSON THOMAS E | 2010-05-04 | — | — | US | disclosed |
| US-20070217965-A1 | Methods, compositions, and apparatuses for forming macrocyclic compounds | JOHNSON THOMAS E | 2007-09-20 | — | — | US | disclosed |