Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SORD | Q00796 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8927591 | 0.81 | GPR119 (0.79) | GPR119KDM4EALDH1A1LMNAHRH3 | |
| SCHEMBL3175103 | 0.80 | GPR119 (0.57) | GPR119KDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8931663 | 0.78 | GPR119 (0.55) | GPR119KDM4EALDH1A1DRD4LMNA | |
| SCHEMBL8931661 | 0.75 | GPR119 (0.52) | GPR119KDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL8931671 | 0.75 | GPR119 (0.51) | GPR119KDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7878334 | 0.75 | SMN1; SMN2 (0.56) | GPR119KDM4EALDH1A1LMNAHRH3 | |
| SCHEMBL8931690 | 0.73 | GPR119 (0.58) | GPR119ALDH1A1DRD2HRH3 | |
| SCHEMBL28690280 | 0.69 | TRIM24 (0.53) | GPR119KDM4EALDH1A1SORDLMNA | |
| SCHEMBL8931740 | 0.69 | ADRA1A (0.48) | GPR119ALDH1A1DRD2HTR1A | |
| SCHEMBL23565168 | 0.68 | ELANE (0.44) | GPR119DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607932-A | Heterocyclic derivatives of azolones | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-03-04 | — | — | US | disclosed |