Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926713 | 0.92 | DGAT1 (0.44) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8931715 | 0.87 | DGAT1 (0.55) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9284187 | 0.84 | MAPT (0.55) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8931713 | 0.83 | DGAT1 (0.64) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9287329 | 0.83 | MAPT (0.64) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8931707 | 0.81 | MAPT (0.54) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8927528 | 0.81 | DGAT1 (0.64) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8931114 | 0.81 | DGAT1 (0.64) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8931712 | 0.81 | MAPT (0.54) | DGAT1MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8931747 | 0.80 | DGAT1 (0.58) | DGAT1MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607932-A | Heterocyclic derivatives of azolones | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-03-04 | — | — | US | disclosed |