Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396997 | 0.97 | APP (0.44) | APPXDHMEN1KMT2AMAPT | |
| SCHEMBL8927611 | 0.87 | APP (0.37) | APPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28396276 | 0.85 | APP (0.42) | APPXDHMEN1KMT2AMAPT | |
| SCHEMBL21979758 | 0.84 | ALDH1A1 (0.41) | APPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28882484 | 0.83 | ACHE (0.46) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8926480 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8927301 | 0.82 | APP (0.41) | APPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9242278 | 0.82 | ALDH1A1 (0.41) | APPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10128556 | 0.81 | CYP1A2 (0.39) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9427929 | 0.80 | CYP1A2 (0.38) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631404-A | DIAMINE COMPOUND SUBSTITUTED WITH PYRENE RING, FLEXIBILITY | RICOH COMPANY, LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5489495-A | Electrophotographic photoconductor and diamine compounds for use in the same | RICHOH COMPANY, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |