Dihydrophenanthrene

Dihydrophenanthrene

SCHEMBL8927840

O=CCCC(=O)O.c1ccc2c(c1)CCc1ccccc1-2

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.47
SRD5A2 P31213 1/20 0.47
RAB9A P51151 2/20 0.44
MITF O75030 1/20 0.44
HSP90AA1 P07900 1/20 0.44
KDM4E B2RXH2 5/20 0.43
TSHR P16473 2/20 0.43
NOTUM Q6P988 2/20 0.43
ALOX15 P16050 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
LMNA P02545 5/20 0.43
ALDH1A1 P00352 4/20 0.43
NPSR1 Q6W5P4 2/20 0.43
GAA P10253 1/20 0.43
CES1 P23141 1/20 0.42
SLC6A2 P23975 4/20 0.41
CYP3A4 P08684 3/20 0.41
CYP1A2 P05177 2/20 0.41
ADRB2 P07550 2/20 0.41
RET P07949 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28382562 0.77 FFAR1 (0.57) RAB9ATSHRLMNAALDH1A1GAA
SCHEMBL503179 0.74 SRD5A2 (0.67) SRD5A1SRD5A2RAB9AMITFHSP90AA1
Toluene SCHEMBL10600992 0.74 KMT2A (0.50) RAB9ATSHRLMNAALDH1A1GAA
Fluorobenzene SCHEMBL10599852 0.74 NR4A2 (0.45) RAB9AKDM4ETSHRLMNAALDH1A1
Chlorobenzene SCHEMBL10599624 0.74 NR4A2 (0.45) RAB9ATSHRLMNAALDH1A1GAA
O-Xylene SCHEMBL27464940 0.74 NR4A2 (0.45) RAB9ATSHRLMNAALDH1A1NPSR1
SCHEMBL3548179 0.74 ALDH1A1 (0.49) SRD5A1SRD5A2KDM4ETSHRNOTUM
SCHEMBL11312659 0.73 HRH1 (0.60) RAB9AKDM4ETSHRLMNAALDH1A1
SCHEMBL7609163 0.73 SLC6A2 (0.65) RAB9AKDM4ETSHRLMNAALDH1A1
SCHEMBL1674816 0.72 SLC6A2 (0.59) RAB9AKDM4ETSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed