SCHEMBL8927908

SCHEMBL8927908

CC(=O)Nc1cc(C)cc(C)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.55
KMT2A Q03164 3/20 0.46
LMNA P02545 2/20 0.46
ALDH1A1 P00352 5/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 1/20 0.45
TSHR P16473 1/20 0.45
MAPT P10636 1/20 0.44
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
LCK P06239 1/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10888761 0.81 ALDH1A1 (0.46) GPR35KMT2ALMNAALDH1A1HPGD
SCHEMBL16134063 0.79 SMN1; SMN2 (0.48) KMT2ALMNAALDH1A1HPGDHTT
SCHEMBL17736225 0.79 GPR35 (0.49) GPR35KMT2AALDH1A1TSHRMEN1
SCHEMBL27753611 0.78 GAA (0.48) KMT2ALMNAALDH1A1HPGDHTT
SCHEMBL28821783 0.78 ALDH1A1 (0.53) GPR35KMT2ALMNAALDH1A1HPGD
SCHEMBL2902943 0.77 ALDH1A1 (0.63) KMT2ALMNAALDH1A1HPGDHTT
SCHEMBL27653431 0.77 ALDH1A1 (0.46) GPR35KMT2ALMNAALDH1A1HPGD
SCHEMBL15765839 0.77 KMT2A (0.68) KMT2ALMNAALDH1A1HPGDHTT
SCHEMBL14354727 0.76 GPR35 (0.44) GPR35KMT2ALMNAALDH1A1HPGD
SCHEMBL10890401 0.74 LMNA (0.54) KMT2ALMNAALDH1A1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631403-A HYDROLYSIS OF HALOCARBOXANILIDE IN SOLVENT HOECHST AG (DE) 1997-05-20 US disclosed