Styrene

Styrene

SCHEMBL8928045

C=C(CC=CC(=O)O)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 1/20 0.45
HDAC3 O15379 1/20 0.43
TNKS O95271 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
PAM P19021 1/20 0.40
PTGER4 P35408 1/20 0.38
PTGER3 P43115 1/20 0.38
PTGER2 P43116 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL31597085 0.84 PAM (0.53) ALDH1A1TSHRHDAC3TNKSHDAC4
Styrene SCHEMBL537154 0.84 ALDH1A1 (0.45) ALDH1A1TSHRHDAC3TNKSHDAC4
Styrene SCHEMBL448561 0.84 ALDH1A1 (0.39) ALDH1A1TSHRHDAC3TNKSHDAC4
Styrene SCHEMBL3223911 0.83 ALDH1A1 (0.52) ALDH1A1TSHRHDAC3TNKSHDAC4
Styrene SCHEMBL28318637 0.83 PAM (0.54) ALDH1A1TSHRHDAC3TNKSHDAC4
Styrene SCHEMBL758736 0.82 ALDH1A1 (0.35) ALDH1A1TSHRHDAC3TNKSHDAC4
Maleic Acid SCHEMBL8841066 0.82 PAM (0.58) ALDH1A1HDAC3TNKSHDAC4HDAC1
Styrene SCHEMBL327751 0.82 CYP3A4 (0.41) ALDH1A1TSHRHDAC3TNKSHDAC4
Styrene SCHEMBL1227877 0.81 ALDH1A1 (0.36) ALDH1A1TSHRHDAC3TNKSHDAC4
SCHEMBL306251 0.80 TSHR (0.44) ALDH1A1TSHRLMNACYP2D6ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650252-A Toner grafting processes XEROX CORPORATION (US) 1997-07-22 US disclosed