Styrene

Styrene

SCHEMBL537154

C=CC=CCC(=C)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45
PAM P19021 1/20 0.40
MAOB P27338 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP3A4 P08684 2/20 0.33
AKR1C3 P42330 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
PTGS2 P35354 1/20 0.33
AKR1C1 Q04828 1/20 0.33
FAAH O00519 1/20 0.32
LMNA P02545 2/20 0.32
AKT1 P31749 1/20 0.32
HDAC3 O15379 1/20 0.32
TNKS O95271 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7169689 0.92 ALDH1A1 (0.38) ALDH1A1TSHRPAMMAOB
Styrene SCHEMBL28318637 0.86 PAM (0.54) ALDH1A1TSHRPAMMAOBCYP2C9
Styrene SCHEMBL28317654 0.85 PAM (0.56) ALDH1A1TSHRPAMMAOBCYP2C9
Styrene SCHEMBL8928045 0.84 ALDH1A1 (0.45) ALDH1A1TSHRPAMMAOBCYP2C9
Styrene SCHEMBL2019985 0.84 ALDH1A1 (0.39) ALDH1A1TSHRPAMMAOBLMNA
Styrene SCHEMBL3223911 0.83 ALDH1A1 (0.52) ALDH1A1TSHRPAMCYP2C9CYP3A4
SCHEMBL1394549 0.82 ALOX15 (0.41) ALDH1A1CYP2D6ALOX15HSD17B10
Styrene SCHEMBL31597085 0.81 PAM (0.53) ALDH1A1TSHRPAMMAOBCYP2C9
Styrene SCHEMBL17836838 0.81 ALDH1A1 (0.39) ALDH1A1TSHRPAMMAOBLMNA
Butadiene SCHEMBL5146753 0.80 PAM (0.59) ALDH1A1PAMMAOBCYP2C9HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3983295-A VINYL CHLORIDE POLYMER, POLYALLYL OR VINYL MONOMER, PEROXIDE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-09-28 US claimed
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
CN-114554844-B Use of silicate in greenhouse films for improving fruit development of plants 索尔维公司 2024-06-07 CN disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 US disclosed
CN-116874967-A Composition, polymer composite article formed therewith, and method of making the same 美国陶氏有机硅公司 2023-10-13 CN disclosed
CN-111433275-B Composition, polymer composite article formed therewith, and method of making the same 美国陶氏有机硅公司 2023-07-25 CN disclosed
US-11485835-B2 Impact resistant cyclic phosphazenes INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-11-01 US disclosed
CN-111630103-B Composition, polymer composite article formed therewith, and method of making same 美国陶氏有机硅公司 2022-10-28 CN disclosed
EP-0695782-B1 Chlorinated polyvinyl chloride compounds having improved stability, toughness and a low rate of heat release and smoke generation GOODRICH CO B F (US) 1998-11-18 EP disclosed
EP-0695782-A1 Chlorinated polyvinyl chloride compounds having improved stability, toughness and a low rate of heat release and smoke generation THE B.F. GOODRICH COMPANY (US) 1996-02-07 EP disclosed
EP-0141107-B1 GLASS REINFORCED POLYAMIDE COMPOSITION CONTAINING ACRYLIC CORE/SHELL POLYMER AlliedSignal Inc. (US) 1989-06-14 EP disclosed
EP-0141107-A2 Glass reinforced polyamide composition containing acrylic core/shell polymer AlliedSignal Inc. (US) 1985-05-15 EP disclosed
US-4495324-A IMPROVED IMPACT STRENGTH ALLIED CORPORATION (US) 1985-01-22 US disclosed
EP-0013485-B1 THERMOPLASTIC POLYGLUTARIMIDE COMPOSITIONS AND METHODS OF MAKING THEM ROHM AND HAAS COMPANY (US) 1983-01-19 EP disclosed
EP-0035341-A2 Blending of vinyl chloride polymer and glutarimide polymer ROHM AND HAAS COMPANY (US) 1981-09-09 EP disclosed
US-4255322-A N-HETEROCYCLIC POLYMERS FROM ACRYLIC POLYMERS, E.G. METHYL METHACRYLATE, MODIFIED BY AMMONIA OR A PRIMARY AMINE; MOLDING MATERIALS; IMPACT STRENGTH ROHM AND HAAS COMPANY (US) 1981-03-10 US disclosed
US-4254232-A BLENDING WITH POLYCARBONATE AND BUTADIENE OR ACRYLATE COPOLYMER ROHM AND HAAS COMPANY (US) 1981-03-03 US disclosed
EP-0013485-A1 Thermoplastic polyglutarimide compositions and methods of making them ROHM AND HAAS COMPANY (US) 1980-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 ALDH1A1 3354/4885TSHR 566/4885PAM 454/4885
US-11485835-B2 Impact resistant cyclic phosphazenes PHOSPHO1, PLCG2, PLCB3 ALDH1A1 3255/4885TSHR 4548/4885PAM 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.