Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634361 | 0.84 | RECQL (0.69) | MTNR1BMTNR1AMEN1KMT2AL3MBTL1 | |
| SCHEMBL24528927 | 0.81 | MTNR1A (0.67) | MTNR1BMTNR1A | |
| SCHEMBL29722609 | 0.81 | MTNR1A (0.67) | MTNR1BMTNR1A | |
| SCHEMBL8928119 | 0.78 | MTNR1A (0.81) | MTNR1BMTNR1A | |
| SCHEMBL8928067 | 0.77 | MTNR1A (0.74) | MTNR1BMTNR1A | |
| SCHEMBL18183659 | 0.77 | HPGD (0.63) | MTNR1A | |
| SCHEMBL19002581 | 0.77 | EPHX2 (0.80) | — | |
| SCHEMBL8928243 | 0.77 | MTNR1A (0.68) | MTNR1BMTNR1AMEN1KMT2A | |
| SCHEMBL1108079 | 0.77 | KMT2A (0.67) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL19624756 | 0.77 | MTNR1A (0.60) | MTNR1BMTNR1AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |