Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409264 | 0.80 | SMN1; SMN2 (0.68) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL28382028 | 0.80 | KMT2A (0.55) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL23119199 | 0.80 | NPC1 (0.75) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL8928226 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BPKMALDH1A1 | |
| SCHEMBL9486768 | 0.79 | MEN1 (0.62) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL8928078 | 0.78 | MTNR1A (0.65) | MTNR1AMTNR1BPKMKMT2A | |
| SCHEMBL9730574 | 0.78 | NPC1 (0.77) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL23050851 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL8928122 | 0.77 | MTNR1B (0.70) | MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL17842262 | 0.77 | RAB9A (0.75) | MTNR1AMTNR1BNPC1PKMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |