Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928491 | 0.93 | OPRK1 (0.47) | OPRK1PDE4DSMN1; SMN2RECQLKDM4E | |
| SCHEMBL8928437 | 0.91 | HPGD (0.41) | SMN1; SMN2RECQLKDM4EHPGDCCKBR | |
| SCHEMBL8928580 | 0.91 | OPRK1 (0.60) | OPRK1PDE4DCYP3A4ALOX15PTAFR | |
| SCHEMBL8928656 | 0.91 | OPRK1 (0.44) | OPRK1PDE4DSMN1; SMN2RECQLHPGD | |
| SCHEMBL8928531 | 0.86 | HPGD (0.41) | SMN1; SMN2RECQLKDM4EHPGDCCKBR | |
| SCHEMBL8928618 | 0.86 | OPRK1 (0.54) | OPRK1PDE4DSMN1; SMN2RECQLKDM4E | |
| SCHEMBL8928508 | 0.85 | OPRK1 (0.50) | OPRK1PDE4DCYP3A4ALOX15PTAFR | |
| SCHEMBL8928915 | 0.85 | OPRK1 (0.62) | OPRK1PDE4DCYP3A4ALOX15PTAFR | |
| SCHEMBL8928620 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2RECQLKDM4EHPGDCCKBR | |
| SCHEMBL8928771 | 0.84 | OPRK1 (0.59) | OPRK1PDE4DMAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |