Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928465 | 0.91 | OPRK1 (0.47) | HPGDSMN1; SMN2RECQLCCKBRNPC1 | |
| SCHEMBL8928511 | 0.91 | PKM (0.42) | HPGDSMN1; SMN2RECQLCCKBRRAB9A | |
| SCHEMBL8928531 | 0.89 | HPGD (0.41) | HPGDSMN1; SMN2RECQLCCKBRNPC1 | |
| SCHEMBL8928620 | 0.86 | SMN1; SMN2 (0.40) | HPGDSMN1; SMN2RECQLCCKBRNPC1 | |
| SCHEMBL8928565 | 0.85 | HPGD (0.45) | HPGDSMN1; SMN2RECQLKDM4E | |
| SCHEMBL8928491 | 0.84 | OPRK1 (0.47) | HPGDSMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL8928542 | 0.83 | OPRK1 (0.46) | — | |
| SCHEMBL8928508 | 0.82 | OPRK1 (0.50) | — | |
| SCHEMBL8928580 | 0.82 | OPRK1 (0.60) | — | |
| SCHEMBL8928656 | 0.82 | OPRK1 (0.44) | HPGDSMN1; SMN2RECQLCCKBRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |