Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928389 | 0.91 | PKM (0.41) | SMN1; SMN2RAB9AMAPTCCKBRBRD4 | |
| SCHEMBL8928437 | 0.86 | HPGD (0.41) | SMN1; SMN2NPC1RAB9AMAPTCCKBR | |
| SCHEMBL8928425 | 0.85 | MAPK1 (0.44) | SMN1; SMN2BRD4KMT2AHPGDRECQL | |
| SCHEMBL8928531 | 0.85 | HPGD (0.41) | SMN1; SMN2NPC1RAB9AMAPTCCKBR | |
| SCHEMBL8928465 | 0.84 | OPRK1 (0.47) | SMN1; SMN2NPC1RAB9AMAPTCCKBR | |
| SCHEMBL8928404 | 0.79 | HPGD (0.41) | SMN1; SMN2MAPTBRD4KDM4EHPGD | |
| SCHEMBL8928542 | 0.78 | OPRK1 (0.46) | — | |
| SCHEMBL8928511 | 0.78 | PKM (0.42) | SMN1; SMN2RAB9AMAPTCCKBRKMT2A | |
| SCHEMBL8928636 | 0.78 | MIF (0.44) | BRD4KDM4E | |
| SCHEMBL8928491 | 0.78 | OPRK1 (0.47) | SMN1; SMN2NPC1RAB9AMAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |