Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.84 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.84 |
| ▸ | PTAFR | P25105 | 19/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469718 | 0.94 | PTAFR (0.88) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9522397 | 0.92 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10462569 | 0.92 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9525077 | 0.92 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9403079 | 0.92 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9525884 | 0.92 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10464347 | 0.92 | PTAFR (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9667837 | 0.92 | OPRK1 (0.81) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL42920 | 0.92 | OPRK1 (1.00) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL30665015 | 0.92 | OPRK1 (1.00) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
| EP-0194416-B1 | THIENO-TRIAZOLO-1,4-DIAZEPINO-2-CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM KG (DE) | 1989-04-26 | — | — | EP | disclosed |