SCHEMBL8928536

SCHEMBL8928536

O=S(=O)(O)c1c(O)ccc2c(O)cccc12.[NaH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.48
IDO1 P14902 3/20 0.44
LDHA P00338 1/20 0.44
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
APP P05067 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
SNCA P37840 1/20 0.43
RECQL P46063 1/20 0.43
AURKA O14965 1/20 0.41
AURKB Q96GD4 1/20 0.41
EP300 Q09472 2/20 0.40
KAT2B Q92831 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
TNNI3 P19429 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14184043 0.85 HSD17B10 (0.40) IDO1LDHAHPGDHSD17B10MAPT
SCHEMBL27566003 0.85 CDK2 (0.53) CDK2IDO1LDHAHPGDHSD17B10
SCHEMBL8113738 0.83 TTR (0.55) CDK2LDHATDP1AURKAAURKB
SCHEMBL21359310 0.81 TTR (0.58) CDK2IDO1LDHAHPGDHSD17B10
SCHEMBL21359416 0.81 LDHA (0.38) CDK2LDHAHSD17B10TDP1TSHR
SCHEMBL7753514 0.81 AURKA (0.54) CDK2IDO1LDHAHPGDHSD17B10
SCHEMBL8928532 0.79 CDK2 (0.47) CDK2IDO1LDHAHPGDHSD17B10
SCHEMBL582872 0.79 ALDH1A1 (0.43) CDK2HPGDHSD17B10TDP1MAPT
SCHEMBL17813876 0.78 CDK2 (0.42) CDK2IDO1LDHAHPGDHSD17B10
SCHEMBL20885914 0.77 ERN1 (0.52) HPGDHSD17B10TDP1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691099-A DISCOLORATION INHIBITION; PRESERVATION; IMAGE QUALITY RICOH COMPANY, LTD. (JP) 1997-11-25 US disclosed