SCHEMBL7753514

SCHEMBL7753514

Nc1ccc2c(O)cccc2c1S(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.54
AURKB Q96GD4 1/20 0.54
CDK2 P24941 1/20 0.50
IDO1 P14902 2/20 0.47
HDAC3 O15379 1/20 0.47
EP300 Q09472 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT8 Q9H7Z6 1/20 0.47
NCOR2 Q9Y618 1/20 0.47
TTR P02766 1/20 0.44
NR4A1 P22736 1/20 0.44
LDHA P00338 1/20 0.42
CA2 P00918 1/20 0.40
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 2/20 0.38
PLAU P00749 1/20 0.38
CYP1A2 P05177 2/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10900215 0.85 TTR (0.61) AURKAAURKBIDO1HDAC3EP300
SCHEMBL313372 0.82 TTR (0.68) AURKAAURKBCDK2TTRNR4A1
SCHEMBL30322685 0.82 TTR (0.68) AURKAAURKBCDK2TTRNR4A1
SCHEMBL8928536 0.81 CDK2 (0.48) AURKAAURKBCDK2IDO1HDAC3
SCHEMBL27566003 0.81 CDK2 (0.53) AURKAAURKBCDK2IDO1TTR
SCHEMBL9274363 0.81 TTR (0.66) AURKAAURKBCDK2TTRNR4A1
SCHEMBL9872607 0.81 CYP1A2 (0.45) AURKAAURKBTTRHSD17B10ALDH1A1
SCHEMBL20514928 0.81 TTR (0.66) AURKAAURKBCDK2TTRNR4A1
SCHEMBL7052180 0.81 TTR (0.66) AURKAAURKBCDK2TTRNR4A1
SCHEMBL9300802 0.80 LDHA (0.47) AURKAAURKBCDK2IDO1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741046-B2 Ink composition, inkjet recording method and colored body NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-06-03 US disclosed
US-20130288019-A1 INK COMPOSITION, INKJET RECORDING METHOD, AND COLORED MATERIAL NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-10-31 US disclosed
US-20130101811-A1 INK COMPOSITION, INKJET RECORDING METHOD AND COLORED BODY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-04-25 US disclosed
CN-101891967-B Method for the reactive colouring of leather BASF SE 2013-02-27 CN disclosed
CN-101891967-A The reactive staining method of leather BASF AG 2010-11-24 CN disclosed
CN-1965125-B Method for the reactive coloration of leather BASF AG 2010-06-09 CN disclosed
CN-1875144-B Reactive colouring of leather BASF AG 2010-05-26 CN disclosed
CN-1965125-A Method for the reactive coloration of leather BASF AG (DE) 2007-05-16 CN disclosed
CN-1875144-A Reactive colouring of leather BASF AG (DE) 2006-12-06 CN disclosed
EP-1075500-A1 WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-02-14 EP disclosed
WO-1999058612-A1 WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-18 WO disclosed
US-5760193-A FOR COTTON, WOOL, POLYAMIDES; HIGH COLOR STRENGTH, COLORFASTNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-06-02 US disclosed
EP-0313513-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-06-17 EP disclosed
EP-0313513-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1989-04-26 EP disclosed
EP-0148121-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
EP-0204244-A2 Tetrakis azo dyes BAYER AG (DE) 1986-12-10 EP disclosed
US-4591634-A GOOD BUILD-UP CAPACITY AND COMBINABILITY BAYER AKTIENGESELLSCHAFT (DE) 1986-05-27 US disclosed
US-4216166-A Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed