Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928671 | 0.91 | LMNA (0.42) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL8929322 | 0.91 | MAPT (0.46) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL14814841 | 0.87 | LTA4H (0.51) | NPC1MAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL29502776 | 0.87 | LTA4H (0.51) | NPC1MAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8769004 | 0.86 | MAPK1 (0.51) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL8929345 | 0.86 | NPC1 (0.55) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL13021253 | 0.81 | NPC1 (0.56) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL8928652 | 0.80 | LMNA (0.43) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL14813417 | 0.79 | MAPT (0.44) | NPC1MAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL29502785 | 0.79 | MAPT (0.44) | NPC1MAPTRAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5649980-A | Process for the photochemical and thermal stabilization of undyed and dyed polyester fibre materials | CIBA-GEIGY CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0584044-A1 | Process for photochemical and thermal stabilization of undyert and dyert polyester fibrous materials | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |