Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | GRK6 | P43250 | 2/20 | 0.44 |
| ▸ | APLNR | P35414 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928563 | 0.89 | NPC1 (0.57) | NPC1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL8928671 | 0.88 | LMNA (0.42) | NPC1ADORA3ADORA1RAB9AALDH1A1 | |
| SCHEMBL8928588 | 0.86 | NPC1 (0.46) | NPC1ADORA3ADORA1RAB9AALDH1A1 | |
| SCHEMBL13030444 | 0.82 | NPC1 (0.77) | NPC1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8767871 | 0.81 | NPC1 (0.62) | NPC1CYP3A4GRK6RAB9AALDH1A1 | |
| SCHEMBL30174369 | 0.81 | NPC1 (0.62) | NPC1CYP3A4GRK6RAB9AALDH1A1 | |
| SCHEMBL12810983 | 0.78 | NPC1 (0.62) | NPC1CYP3A4GRK6RAB9AALDH1A1 | |
| SCHEMBL14747697 | 0.77 | NPC1 (0.70) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL19756251 | 0.77 | NPC1 (0.70) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8929322 | 0.77 | MAPT (0.46) | NPC1GRK6RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5649980-A | Process for the photochemical and thermal stabilization of undyed and dyed polyester fibre materials | CIBA-GEIGY CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0584044-A1 | Process for photochemical and thermal stabilization of undyert and dyert polyester fibrous materials | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |