Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170428 | 0.86 | MEN1 (0.68) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30614510 | 0.86 | MEN1 (0.68) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6418353 | 0.85 | MEN1 (0.66) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| Ethane SCHEMBL27458330 | 0.85 | MEN1 (0.66) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| Water SCHEMBL10865815 | 0.85 | MEN1 (0.66) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31045486 | 0.79 | MCHR1 (0.53) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28259240 | 0.79 | MEN1 (0.59) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| Acetic Acid SCHEMBL8159401 | 0.77 | PDE10A (0.60) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| Toluene SCHEMBL27569075 | 0.77 | LMNA (0.57) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27453447 | 0.77 | RAB9A (0.61) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790249-A1 | Enantiopure quinuclidine derivatives and process for their preparation | Buchler GmbH (DE) | 1997-08-20 | — | — | EP | disclosed |