Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 17/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928438 | 0.89 | OPRK1 (0.51) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928403 | 0.89 | OPRK1 (0.49) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928456 | 0.88 | OPRK1 (0.63) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928529 | 0.88 | OPRK1 (0.47) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928448 | 0.88 | OPRK1 (0.49) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928542 | 0.87 | OPRK1 (0.46) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928537 | 0.87 | OPRK1 (0.54) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928635 | 0.86 | PTAFR (0.44) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928565 | 0.84 | HPGD (0.45) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928587 | 0.84 | PTAFR (0.46) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |