Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 11/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928618 | 0.91 | OPRK1 (0.54) | HPGDOPRK1PDE4DRECQLSMN1; SMN2 | |
| SCHEMBL8928406 | 0.86 | OPRK1 (0.53) | HPGDOPRK1PDE4DRECQLSMN1; SMN2 | |
| SCHEMBL8928425 | 0.86 | MAPK1 (0.44) | HPGDOPRK1PDE4DRECQLSMN1; SMN2 | |
| SCHEMBL8928500 | 0.86 | MAPK1 (0.43) | HPGDOPRK1RECQLSMN1; SMN2MAPK1 | |
| SCHEMBL8928437 | 0.85 | HPGD (0.41) | HPGDRECQLSMN1; SMN2KDM4E | |
| SCHEMBL8928456 | 0.84 | OPRK1 (0.63) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928625 | 0.84 | OPRK1 (0.47) | OPRK1PDE4DMAPK1PTAFRCYP3A4 | |
| SCHEMBL8928371 | 0.84 | HPGD (0.45) | HPGDOPRK1PDE4DRECQLSMN1; SMN2 | |
| SCHEMBL8928448 | 0.84 | OPRK1 (0.49) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928438 | 0.84 | OPRK1 (0.51) | OPRK1PDE4DMAPK1PTAFRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |