Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 14/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928854 | 0.92 | OPRK1 (0.44) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928542 | 0.91 | OPRK1 (0.46) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928545 | 0.90 | OPRK1 (0.47) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928504 | 0.90 | OPRK1 (0.56) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928625 | 0.86 | OPRK1 (0.47) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928706 | 0.84 | OPRK1 (0.45) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928511 | 0.83 | PKM (0.42) | PKMMAPK1RAB9ACASRMAPT | |
| SCHEMBL8928915 | 0.82 | OPRK1 (0.62) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928656 | 0.82 | OPRK1 (0.44) | OPRK1PDE4DPKMMAPK1RAB9A | |
| SCHEMBL8929052 | 0.82 | OPRK1 (0.58) | PTAFROPRK1PDE4DCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |