Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954264 | 0.97 | BRD4 (0.35) | BRD4BRD9GAAL3MBTL1TP53 | |
| SCHEMBL8928693 | 0.83 | BRD4 (0.33) | BRD4BRD9GAAL3MBTL1TP53 | |
| SCHEMBL7955910 | 0.82 | RORC (0.38) | BRD4BRD9GAATP53MAPT | |
| SCHEMBL7954261 | 0.82 | BRD4 (0.36) | BRD4BRD9L3MBTL1TP53MAPT | |
| SCHEMBL7955723 | 0.81 | BRD4 (0.32) | BRD4BRD9L3MBTL1TP53MAPT | |
| SCHEMBL7966685 | 0.78 | BRD4 (0.31) | BRD4BRD9 | |
| Water SCHEMBL7954095 | 0.78 | MAPT (0.31) | L3MBTL1TP53MAPTALDH1A1THRB | |
| SCHEMBL7958093 | 0.77 | — | — | |
| SCHEMBL7954114 | 0.76 | — | — | |
| SCHEMBL7947181 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |