Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954261 | 0.96 | BRD4 (0.36) | BRD4BRD9TP53MAPTRXFP1 | |
| SCHEMBL7946966 | 0.89 | BRD4 (0.31) | BRD4BRD9 | |
| SCHEMBL7955910 | 0.84 | RORC (0.38) | BRD4BRD9TP53MAPTRXFP1 | |
| SCHEMBL8928699 | 0.83 | BRD4 (0.33) | BRD4BRD9TP53MAPTRXFP1 | |
| SCHEMBL7954264 | 0.81 | BRD4 (0.35) | BRD4BRD9TP53MAPTGAA | |
| SCHEMBL7955719 | 0.80 | BRD4 (0.33) | BRD4BRD9TP53MAPTRXFP1 | |
| SCHEMBL7958083 | 0.79 | PDE3B (0.39) | BRD4MAPTSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL8414704 | 0.79 | RAB9A (0.32) | TP53MAPTSMN1; SMN2GAAPOLB | |
| SCHEMBL7955914 | 0.79 | BRD4 (0.33) | BRD4BRD9 | |
| SCHEMBL6798475 | 0.79 | BRD4 (0.31) | BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |