Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958083 | 0.86 | PDE3B (0.39) | GAAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8928693 | 0.84 | BRD4 (0.33) | RORCGAAALDH1A1TP53MAPT | |
| SCHEMBL8928699 | 0.82 | BRD4 (0.33) | GAAKMT2AALDH1A1TP53MAPT | |
| SCHEMBL7954261 | 0.81 | BRD4 (0.36) | KMT2AALDH1A1TP53MAPTKDM4E | |
| SCHEMBL7954264 | 0.80 | BRD4 (0.35) | GAAKMT2AALDH1A1TP53MAPT | |
| SCHEMBL7946966 | 0.72 | BRD4 (0.31) | BRD4BRD9 | |
| SCHEMBL7958065 | 0.65 | ALDH1A1 (0.44) | GAAKMT2AALDH1A1TP53MAPT | |
| SCHEMBL6801919 | 0.63 | ALDH1A1 (0.42) | GAAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL29406091 | 0.61 | SLC9A1 (0.42) | KMT2AALDH1A1TP53MEN1RAB9A | |
| SCHEMBL7946984 | 0.61 | PDE3B (0.45) | MCL1GAAKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271251-B1 | CARDIOVASCULAR DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2001-08-07 | — | — | US | disclosed |