Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 8/20 | 0.43 |
| ▸ | NAMPT | P43490 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.39 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928679 | 0.87 | MIF (0.45) | MIFOPRK1HTR2CDRD2DRD3 | |
| SCHEMBL8928848 | 0.84 | OPRK1 (0.44) | MIFOPRK1HTR2CDRD2DRD3 | |
| SCHEMBL8928781 | 0.83 | MIF (0.46) | MIFOPRK1HTR2CKDM4EHSD17B10 | |
| SCHEMBL8928404 | 0.81 | HPGD (0.41) | BRD4OPRK1KDM4E | |
| SCHEMBL8928876 | 0.81 | MEN1 (0.37) | BRD4 | |
| SCHEMBL8928590 | 0.78 | OPRK1 (0.46) | MIFBRD4NAMPTOPRK1HTR2C | |
| SCHEMBL8928429 | 0.78 | MEN1 (0.35) | BRD4KDM4EHSD17B10 | |
| SCHEMBL8928620 | 0.78 | SMN1; SMN2 (0.40) | BRD4KDM4E | |
| SCHEMBL8928425 | 0.78 | MAPK1 (0.44) | BRD4OPRK1 | |
| SCHEMBL8928549 | 0.77 | MIF (0.43) | MIFOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |