SCHEMBL8928864

SCHEMBL8928864

CC(=O)Nc1cccc(O)c1C#N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
MAPT P10636 3/20 0.43
POLB P06746 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
KDM4E B2RXH2 4/20 0.41
MAOA P21397 1/20 0.41
APOBEC3A P31941 1/20 0.41
GFER P55789 1/20 0.41
HDAC1 Q13547 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 2/20 0.41
GAA P10253 2/20 0.41
KMT2A Q03164 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13414547 0.89 ALDH1A1 (0.52) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL9631166 0.83 ALDH1A1 (0.59) ALDH1A1HPGDPOLBNPC1RAB9A
SCHEMBL10767715 0.81 TAS1R3 (0.46) ALDH1A1HPGDMAPTPOLBKDM4E
SCHEMBL28483643 0.81 TAS1R3 (0.56) ALDH1A1HPGDPOLBNPC1RAB9A
SCHEMBL13424871 0.78 POLB (0.44) ALDH1A1HPGDPOLBNPC1RAB9A
SCHEMBL6826636 0.76 HTT (0.57) ALDH1A1HPGDMAPTPOLBNPC1
Hydrochloric Acid SCHEMBL11777356 0.76 GAA (0.59) ALDH1A1HPGDMAPTPOLBNPC1
Water SCHEMBL28741391 0.76 GAA (0.59) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL19004112 0.76 ALDH1A1 (0.53) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL8882492 0.76 ALDH1A1 (0.53) ALDH1A1HPGDMAPTPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57189130-A None JP disclosed
US-5691099-A DISCOLORATION INHIBITION; PRESERVATION; IMAGE QUALITY RICOH COMPANY, LTD. (JP) 1997-11-25 US disclosed
US-5556733-A COUPLER RICOH COMPANY, LTD. (JP) 1996-09-17 US disclosed
US-4467024-A Process for the production of thermo-developable type diazo copying material RICOH CO., LTD. (JP) 1984-08-21 US disclosed
US-4400456-A FATTY ACID AMIDE COLOR ASSIST, HIGH DENSITY IMAGES RICOH CO., LTD. (JP) 1983-08-23 US disclosed
JP-S57189130-A MANUFACTURE OF HEAT DEVELOPABLE TYPE DIAZO COPYING MATERIAL RICOH CO LTD 1982-11-20 JP disclosed