Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13414547 | 0.84 | ALDH1A1 (0.52) | POLBCYP2C19ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9631166 | 0.78 | ALDH1A1 (0.59) | POLBCYP2C19ALDH1A1HPGDGAA | |
| SCHEMBL27833609 | 0.78 | POLB (0.57) | POLBPLK1ALDH1A1GAAKMT2A | |
| SCHEMBL8928864 | 0.78 | ALDH1A1 (0.46) | POLBCYP2C19ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13424895 | 0.76 | POLB (0.46) | POLBPLK1ALDH1A1HPGDGAA | |
| SCHEMBL28483643 | 0.76 | TAS1R3 (0.56) | POLBCYP2C19ALDH1A1HPGDTAS1R3 | |
| SCHEMBL10767715 | 0.76 | TAS1R3 (0.46) | POLBCYP2C19ALDH1A1HPGDTAS1R3 | |
| SCHEMBL13424880 | 0.72 | SLC6A2 (0.55) | POLBCYP2C19ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6826636 | 0.72 | HTT (0.57) | POLBCYP2C19ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8882492 | 0.71 | ALDH1A1 (0.53) | POLBCYP2C19ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | POLB 4533/4885CYP2C19 1120/4885PLK1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.